Nucleic-acid-templated synthesis as a model system for ancient translation.

نویسندگان

  • Christopher T Calderone
  • David R Liu
چکیده

The translation of nucleic acids into synthetic structures with expanded functional potential has been the subject of considerable research, with applications including small-molecule and polymer evolution, reaction discovery and sensing. Here, we review properties of nucleic-acid-templated synthesis in the context of requirements for prebiotic translation. This analysis highlights the chemical possibilities of ancient translation systems, as well as challenges that these systems may have faced.

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عنوان ژورنال:
  • Current opinion in chemical biology

دوره 8 6  شماره 

صفحات  -

تاریخ انتشار 2004